CRISPR

YearCitationPublication TypeAuthors
2019CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of HSPCs and iPSCs of severe congenital neutropenia patients. (European Hematology Association [EHA] Meeting Abstracts). 2019AbstractNasri M, Ritter M, Mir P, Dannenmann B, Amend D, Makaryan V, Xu Y, Zeidler C, Dale DC, Klimiankou M, Welte K, Skokowa J.
2018CRISPR/Cas9 knock-in HL60 cells closely simulate cellular and functional abnormalities of ELANE associated Neutropenia; Phenotype rescue with MK- 0339 Neutrophil Elastase inhibitor. (ASH Annual Meeting Abstracts). Blood 2018AbstractMakaryan V, Fletcher B, Kelley ML, Nasri M, Skokowa J, Welte K, MD2, Dale DC.